| 发明名称 |
Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases |
| 摘要 |
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal. |
| 申请公布号 |
US8785395(B2) |
申请公布日期 |
2014.07.22 |
| 申请号 |
US201113643592 |
申请日期 |
2011.05.03 |
| 申请人 |
The Texas A & M University System;Temple Therapeutics, Inc. |
发明人 |
Prockop Darwin J.;Oh Joo Youn;Roddy Gavin W.;Rosa Robert;Berkowitz Barry A. |
| 分类号 |
A61K38/00;A61P27/02 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
Olstein Elliot M.;Lillie Raymond J. |
| 主权项 |
1. A method of treating an injury to the cornea in a patient, comprising:
administering to said patient a therapeutic agent for treating an injury to the cornea consisting of TSG-6 protein or a biologically active fragment, or variant thereof, wherein said TSG-6 protein or biologically active fragment, or variant thereof is administered in an amount effective to treat said injury to the cornea in said patient. |
| 地址 |
College Station TX US |
