| 发明名称 |
ISOMIGRASTATIN ANALOGS IN THE TREATMENT OF CANCER |
| 摘要 |
The present invention provides compounds having formula (I): (I) wherein n, R1-R5, Ra-Rb, Q, Y1 and Y2 are as defined herein; and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving increased angiogenesis. |
| 申请公布号 |
CA2582766(C) |
申请公布日期 |
2014.07.22 |
| 申请号 |
CA20052582766 |
申请日期 |
2005.09.23 |
| 申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
发明人 |
DANISHEFSKY, SAMUEL J.;MANDAL, MIHIRBARAN;DORN, DAVID C.;MOORE, MALCOLM A. S. |
| 分类号 |
C07D313/00;A61K31/365;A61P35/00 |
主分类号 |
C07D313/00 |
| 代理机构 |
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