Functional imaging

摘要

A method includes generating a kinetic parameter value for a VOI in a functional image of a subject based on motion corrected projection data using an iterative algorithm, including determining a motion correction for projection data corresponding to the VOI based on the VOI, motion correcting the projection data corresponding to the VOI to generate the motion corrected projection data, and estimating the at least one kinetic parameter value based on the motion corrected projection data or image data generated with the motion corrected projection data. In another embodiment, a method includes registering functional image data indicative of tracer uptake in a scanned patient with image data from a different imaging modality, identifying a VOI in the image based on the registered images, generating at least one kinetic parameter for the VOI, and generating a feature vector including the at least one generated kinetic parameter and at least one bio-marker.

主权项

1. A method, comprising:
(a) determining a motion correction estimate for projection data corresponding to a volume of interest (VOI) in a functional image of a subject based on the VOI; (b) motion correcting the projection data corresponding to the VOI with the motion corrected estimate to generate current motion corrected projection data; (c) estimating at least one kinetic parameter value based on the current motion corrected projection data, wherein the at least one kinetic parameter value; is a current kinetic parameter value: (e) determining a next motion correction estimate for the current corrected projection data corresponding to the VOI based on the VOI; (f) motion correcting the current corrected projection data corresponding to the VOI with the next motion corrected estimated to update the current motion corrected projection data; (g) setting the current motion corrected projection data equal to the updated current motion corrected projection data; and (h) estimating a next kinetic parameter value based on the current motion corrected projection data.