Method for diagnosing gram-negative infections

摘要

The invention concerns an in vitro method for determining if an individual is infected by a gram-negative bacterium preferably on prosthesis comprising: (i) detection of antibodies directed against a polypeptide of sequence SEQ ID NO: 2 and antibodies directed against a polypeptide of sequence SEQ ID NO: 4, in a biological sample of the individual, and (ii) deduction therefrom that the individual is infected by a gram-negative bacterium. The invention further concerns the kit for diagnosing of such an infection.

主权项

1. An in vitro method of determining if an individual is infected by a gram-negative bacterium, the method comprising:
(a) detecting antibodies specific to the polypeptide of SEQ ID NO: 2 and antibodies specific to the polypeptide of SEQ ID NO: 4 in a biological sample of the individual, wherein the biological sample is selected from the group consisting of blood, serum, and plasma, and (b) deducing therefrom that the individual is infected by the gram-negative bacterium, wherein said infection is a biofilm-associated infection and the gram-negative bacterium is from a family selected from the group consisting of Enterobacteriaceae, Pasteurellaceae, and Pseudomonadaceae.