发明名称 Anti-VEGFR-3 antibody compositions
摘要 The present invention provides anti-VEGFR-3 monoclonal antibodies, pharmaceutical compositions containing said antibodies and uses of said antibodies in the treatment of disease.
申请公布号 US8784818(B2) 申请公布日期 2014.07.22
申请号 US201313888716 申请日期 2013.05.07
申请人 ImClone LLC 发明人 Pytowski Bronislaw;Persaud Krishnadatt;Zayek Nathalie
分类号 A61K39/395;C07K16/28 主分类号 A61K39/395
代理机构 代理人 Hason Averie K.
主权项 1. A method of treating cancer in a mammal in need thereof, comprising administering to said mammal an antibody that binds to human VEGFR-3 comprising a LCDR1 of SEQ ID NO: 1, a LCDR2 of SEQ ID NO: 2, a LCDR3 of SEQ ID NO: 3, a HCDR1 of SEQ ID NO: 6, a HCDR2 of SEQ ID NO: 7 and a HCDR3 of SEQ ID NO: 8, wherein the cancer is colon cancer.
地址 Indianapolis IN US