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1. A compound of formula (I)wherein
R represents
a group of formula (1) wherein R1 represents H, a straight or branched (C1-C6) alkyl group or a —(CH2)m—R2 group with R2 selected from the group consisting of hydrogen, halogen, OH, N3, NH2, epoxy groups, leaving groups and carbonyl groups and m is an integer from 0 to 5, represents a double or a triple bond,p being equal to 0 when is a triple bond and equal to 1 when is a double bond or,R=R2 with R2 selected from the group consisting of hydrogen, halogen, OH, N3, NH2, epoxy groups and analogs, leaving groups, leaving groups involved into a transmetalation step catalyzed by Pd(0), and carbonyl groups, n is an integer from 0 to 5 X and Y independently of each other represent hydrogen, halogen or a straight or branched (C1-C6)alkyl group or an hydroxymethyl group, and R′ and R″ independently of each other
represent a group selected from the group consisting of
an oxymethylcarbonyl group of formula (2) whereinR1 and R′1 are independently of each other hydrogen or (C1-C4)alkyl group andR′2 is a straight or branched (C1-C6)alkyl group or straight or branched (C1-C6)alkoxy groupwith the proviso that when R is cis-propenyl n=0 and R′2 is methyl, then R1 and R′1 are not simultaneously hydrogen,a thioethylcarbonyl group of formula (3) whereinR3 is a straight or branched (C1-C6) alkyl groupa lipohilic chain selected from the group consisting of hexadecyloxypropyl (HDP)-, octadecyloxyethyl-, oleyloxypropyl-, and oleyloxyethyl-esters with the proviso that when n=0 then R is not the cis-propenyl orR′ and R″ form with the phosphate atom to which they are linked a cycloalkyle group of formula (4) wherein R4, R5, R6, and R7 each independently represent a straight or branched (C1-C6)alkyl or aryl group or R4 and R7 independently represent a straight or branched (C1-C6) alkyl or aryl group or R5 and R6 form together an aromatic ring, said aromatic ring being optionally substitutedwith the proviso that are excluded. |
