发明名称 |
Treating post-seizure patients |
摘要 |
Patients are subject to a post-seizure treatment regime to separately inhibitor consecutive targets of an epileptogenic cascade comprising neurotransmitter receptor signaling, kinase/phosphatase activity, protein translation, and apoptosis or inflammation. |
申请公布号 |
US8785446(B2) |
申请公布日期 |
2014.07.22 |
申请号 |
US201012688892 |
申请日期 |
2010.01.17 |
申请人 |
Children's Medical Center Corporation |
发明人 |
Jensen Frances E.;Rakhade Sanjay N. |
分类号 |
A61K31/47;A61K31/498;A61K31/18;A61K31/366 |
主分类号 |
A61K31/47 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A therapeutic method for treating a patient post-seizure comprising administering to the patient NBQX (2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione), KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine), and rapamycin. |
地址 |
Boston MA US |