发明名称 |
Combination/association of adapalene and benzoyl peroxide for treating acne lesions |
摘要 |
Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO). |
申请公布号 |
US8785420(B2) |
申请公布日期 |
2014.07.22 |
申请号 |
US201213351986 |
申请日期 |
2012.01.17 |
申请人 |
Galderma Research & Development |
发明人 |
Abou Chacra Vernet Marie-Line;Gross Denis;Loesche Christian;Poncet Michel |
分类号 |
A61K31/60;A61P17/10;A61K31/235;A61K31/70 |
主分类号 |
A61K31/60 |
代理机构 |
Dentons US LLP |
代理人 |
Dentons US LLP |
主权项 |
1. A regimen for the therapeutic treatment of acne lesions, the regimen comprising topically applying to the skin of a subject in need of said treatment, as active ingredients, 0.1% to 0.3% adapalene and 2.5% benzoyl peroxide, combined at fixed doses in a single formula that delivers said active ingredients together synergistically to achieve, in a group of such subjects, a degree of success of at least about 20%, wherein said single formula is applied once daily for a period of 12 weeks. |
地址 |
Biot FR |