发明名称 |
Fremgangsmåder til fremstilling af protein under anvendelse af anti-senescensforbindelser |
摘要 |
Methods of producing a protein in cell culture comprising an anti-senescence compound, such as the antioxidant carnosine, are provided. According to teachings of the present invention, cells grown in a cell culture medium comprising an anti-senescence compound exhibit increased viability and productivity. Furthermore, cell cultures grown in the presence of an anti-senescence compound exhibit decreased levels of high molecular weight aggregates in the cell culture medium. |
申请公布号 |
DK1941026(T3) |
申请公布日期 |
2014.07.21 |
申请号 |
DK20060844211T |
申请日期 |
2006.10.24 |
申请人 |
WYETH LLC |
发明人 |
LUAN, YEN-TUNG;WANG, WENGE;THODAY, PAUL;DRAPEAU, DENIS;CHOU, JUDY |
分类号 |
C12N5/071 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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