| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to immunology and medicine. What is presented is a method for preventing or treating an ocular condition related to high expression or activity of a complement factor D involving administering an antibody or its antigen-binding fragment into an individual. There are presented an anti-factor D 20D12 antibody and its antigen-binding fragment to be used to prepare a therapeutic agent, as well as containing the above antibody or its antigen-binding fragment, a kit for treating the ocular condition related to high activity or expression of factor D.EFFECT: invention can find further application in therapy of the complement system related diseases.14 cl, 6 dwg, 3 tbl |
