| 发明名称 |
PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER |
| 摘要 |
The present invention provides MDM2 inhibitor compounds of Formula IE,
which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor. |
| 申请公布号 |
KR20140091009(A) |
申请公布日期 |
2014.07.18 |
| 申请号 |
KR20147013519 |
申请日期 |
2011.06.03 |
| 申请人 |
AMGEN INC. |
发明人 |
BARTBERGER MICHAEL DAVID;GONZALEZ BUENROSTRO ANA;BECK HILARY PLAKE;CHEN XIAOQI;CONNORS RICHARD VICTOR;DEIGNAN JEFFREY;DUQUETTE JASON;EKSTEROWICZ JOHN;FISHER BENJAMIN;FOX BRIAN MATTHEW;FU JIASHENG;FU ZICE;GONZALEZ LOPEZ DE TURISO FELIX;GRIBBLE JR. MICHAEL WILLIAM;GUSTIN DARIN JAMES;HEATH JULIE ANNE;HUANG XIN;JIAO XIANYUN;JOHNSON MICHAEL;KAYSER FRANK;KOPECKY DAVID JOHN;LAI SUJEN;LI YIHONG;LI ZHIHONG;LIU JIWEN;LOW JONATHAN DANTE;LUCAS BRIAN STUART;MA ZHIHUA;MCGEE LAWRENCE;MCINTOSH JOEL;MCMINN DUSTIN;MEDINA JULIO CESAR;MIHALIC JEFFREY THOMAS;OLSON STEVEN HOWARD;REW, YO SUP;ROVETO PHILIP MARLEY;SUN DAQING;WANG XIAODONG;WANG YINGCAI;YAN XUELEI;YU MING;ZHU JIANG |
| 分类号 |
C07D211/76;A61K31/45;A61P35/00 |
主分类号 |
C07D211/76 |
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