发明名称 Compuestos derivados de (4-fenilimidazol-2-il)etilamina, como moduladores de canal de sodio; composicion farmaceutica que los comprende; y su uso en el tratamiento del dolor.
摘要 <p>The present invention is directed to imidazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new imidazole NaV1.8 modulators of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. NaV1.8 modulators are useful in the treatment of a wide range of disorders, particularly pain.</p>
申请公布号 CL2014000956(A1) 申请公布日期 2014.07.18
申请号 CL20140000956 申请日期 2014.04.14
申请人 PFIZER LIMITED 发明人 BAGAL, SHRANJEET KAUR;KEMP, MARK IAN;MILLER, DUNCAN CHARLES;MURATA, YOSHIHISA
分类号 C07D405/06;A61K31/417;A61P29/00 主分类号 C07D405/06
代理机构 代理人
主权项
地址