发明名称 |
METHOD FOR PREPARING INDOBUFEN USING MICRO FLOW REACTOR |
摘要 |
The present invention relates to a method for producing indobufen using ethyl 2-(4-aminophenyl)acetate, which can be industrially purchased, as a starting material and a method for applying the same to a micro flow reactor. According to the present invention, by producing indobufen using a micro flow reactor, the yield and purity of the produced indobufen can be improved, and time spent for the overall production procedure can be reduced. Accordingly, harmful compounds used during the production procedure can be stably used. |
申请公布号 |
KR20140090822(A) |
申请公布日期 |
2014.07.18 |
申请号 |
KR20130002900 |
申请日期 |
2013.01.10 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
JEONG, JIN HYUN;CHOI, YONG SUNG;LEE, BYUNG JOO |
分类号 |
C07D209/46;A61K31/4035;A61P7/02;A61P9/00 |
主分类号 |
C07D209/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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