发明名称 TRIAZOLE-LINKED CYCLIC DINUCLEOTIDE ANALOGUE
摘要 <p>Provided is a means for improving the chemical stability and lipid solubility of an artificial cyclic nucleoside linked body, which is an analogue of a naturally-occurring-type cyclic dinucleotide, while keeping the structural similarity to the naturally-occurring-type one. The present invention relates to a cyclic dinucleotide analogue having two nucleoside moieties each of which contains a purine base or a pyrimidine base and two linking groups each of which contains a 1,2,3-triazole ring and which link the two nucleoside moieties to each other to form a cyclic structure.</p>
申请公布号 WO2014109256(A1) 申请公布日期 2014.07.17
申请号 WO2013JP85042 申请日期 2013.12.27
申请人 TOHOKU UNIVERSITY 发明人 ISOBE HIROYUKI;FUJINO TOMOKO;OKADA KOHDAI
分类号 C07H19/06;C07H19/16 主分类号 C07H19/06
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