发明名称 |
Engineered dendritic cells and uses for the treatment of cancer |
摘要 |
This invention provides the field of therapeutics. Most specifically present invention provides methods of generating in vitro engineered dendritic cells conditionally expressing interleukin-12 (IL- 12) under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals including human. |
申请公布号 |
AU2008311292(B2) |
申请公布日期 |
2014.07.17 |
申请号 |
AU20080311292 |
申请日期 |
2008.10.08 |
申请人 |
INTREXON CORPORATION;UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
BRAUGHLER, J. MARK;KUMAR, PRASANNA;OKADA, HIDEHO;STORKUS, WALTER J. |
分类号 |
C12N5/00;C12N5/02;C12N5/0784;C12N15/00 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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