发明名称 PLECTIN-1 TARGETED AGENTS FOR DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA
摘要 PROBLEM TO BE SOLVED: To provide compositions for cancer cell biomarkers, such as pancreatic ductal adenocarcinoma (PDAC) cell biomarkers, and binding molecules for diagnosis and treatment of cancer, e.g., PDAC.SOLUTION: A peptide ligand comprises: a first portion comprising a plectin-1 binding moiety; and a second portion coupled to the first portion. The second portion comprises a detectable moiety or a therapeutic agent.
申请公布号 JP2014132021(A) 申请公布日期 2014.07.17
申请号 JP20140042379 申请日期 2014.03.05
申请人 GENERAL HOSPITAL CORP 发明人 KIMBERLY KELLY;RALPH WEISSLEDER;NABEEL BARDEESY
分类号 C07K7/06;A61K38/00;A61K49/00;A61P1/18;A61P35/00;C12N15/09;G01N33/532 主分类号 C07K7/06
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