| 发明名称 |
ANDROGEN RECEPTOR MODULATOR AND USES THEREOF |
| 摘要 |
Described herein is the androgen receptor modulator of formula (I);;in the treatment of prostate cancer in combination with other therapeutic options and in the treatment of diseases or conditions that are amenable to treatment with the androgen receptor modulator, as well as pharmaceutical compositions and medicaments that include such compound. |
| 申请公布号 |
US2014199236(A1) |
申请公布日期 |
2014.07.17 |
| 申请号 |
US201414151106 |
申请日期 |
2014.01.09 |
| 申请人 |
ARAGON PHARMACEUTICALS, INC. |
发明人 |
CHEN ISAN;HAGER JEFFREY H.;MANEVAL EDNA CHOW;HERBERT MARK R.;SMITH NICHOLAS D. |
| 分类号 |
C07D401/04;A61K31/5377;A61K31/436;A61K31/58;A61K31/4025;A61K39/395;A61K51/02;A61K51/10;A61K31/337;A61K31/4439;A61K38/09 |
主分类号 |
C07D401/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a male human patient having advanced castration-sensitive prostate cancer, castration-resistant prostate cancer, or high-risk localized prostate cancer comprising administering the compound of Formula (I), or a pharmaceutically acceptable salt thereof, at a dose in a range of from about 30 mg per day to about 480 mg per day to a male human patient in need of such treatment. |
| 地址 |
SAN DIEGO CA US |
