| 摘要 |
<p>Methods and devices that provide scalable extrusion of cultured cells for use in forming three-dimensional tissue structures. In particular, described herein are methods for preparing and continuously extruding a compacted multicellular body material that may be used to form bioengineered tissue structures. Also described are extrusion tip assemblies that are adapted to receive a suspension of cellular material, and can be used both to prepare the cellular material (e.g. compaction) and to extrude the cellular material in an efficient manner for forming tissue structures.</p> |
