发明名称 CYP450 LIPID METABOLITES REDUCE INFLAMMATION AND ANGIOGENESIS
摘要 Methods for reducing angiogenesis, inflammation, and vascular permeability in a subject by administering an epoxymetabolite of Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA), e.g., as listed in Table A, e.g., one or both of 17,18- epoxyeicosatetraenoic acid (EEQ) and 19,20-epoxydocosapentaenoic acid (EDP), e.g., for the treatment of conditions associated with inflammation or excess angiogenesis or neovascularization, including age-related macular degeneration, cancer, stroke, and arthritis.
申请公布号 CA2930987(A1) 申请公布日期 2014.07.17
申请号 CA20142930987 申请日期 2014.01.09
申请人 MASSACHUSETTS EYE AND EAR INFIRMARY 发明人 CONNOR, KIP M.;YANAI, RYOJI
分类号 A61K31/202;A61P9/02;A61P19/02;A61P27/02;A61P29/00;A61P35/00 主分类号 A61K31/202
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