发明名称 |
TANNIN-CONTAINING GASTROINTESTINAL FORMULATIONS AND METHODS OF USE |
摘要 |
Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition. |
申请公布号 |
US2014200266(A1) |
申请公布日期 |
2014.07.17 |
申请号 |
US201414152267 |
申请日期 |
2014.01.10 |
申请人 |
Wisconsin Alumni Research Foundation |
发明人 |
Reed Jess Dreher;Shanmuganayagam Dhanansayan;Krueger Christian Gerald;Kudsk Kenneth Allan;Pierre Joseph Francis;Heneghan Aaron F.;Feliciano Rodrigo P. |
分类号 |
A61K31/353 |
主分类号 |
A61K31/353 |
代理机构 |
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代理人 |
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主权项 |
1. A method to attenuate negative effects of enteral or parenteral nutrition on intestinal barrier function comprising administering an effective amount of one or more proanthocyanidins to a subject receiving enteral nutrition or parenteral nutrition. |
地址 |
Madison WI US |