发明名称 METHYLATION BIOMARKERS FOR OVARIAN CANCER
摘要 Different combinations of methylation status based biomarkers can be used to test for ovarian cancer with high sensitivity and high specificity.
申请公布号 US2014199696(A1) 申请公布日期 2014.07.17
申请号 US201414153651 申请日期 2014.01.13
申请人 King Abdullah University of Science and Technology 发明人 Mansour Hicham;Incitti Roberto;Bajic Vladimir
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A highly specific and highly selective method of detecting ovarian cancer in a patient, comprising: obtaining a DNA sample from the patient; and measuring, from the DNA sample, a methylation level in a regulatory region of each gene in a plurality of genes selected from the group consisting of: CYP39A1, DAPK1, CAV1, ARMCX1, ROCK1, CDKN1B, MLH1, MED1, PEG3, BEX4, SFRP1, CCND2, SPARCL1, ARMCX2, PLAGL1, RAD51C, SOCS2, RARRES1, UCHL1 and DIRAS3.
地址 Thuwal SA
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