发明名称 |
METHODS FOR MODULATING TAL SPECIFICITY |
摘要 |
Methods for improving or modulating targeting specificity of TALE proteins by introducing alternative RVDs into their modular nucleic acid binding domains. Polynucleotides encoding TALE proteins having alternative targeting specificity towards a nucleic acid target sequence. TALE proteins having alternative targeting specificity towards a nucleic acid target sequence and methods of making and using them. |
申请公布号 |
WO2014033556(A3) |
申请公布日期 |
2014.07.17 |
申请号 |
WO2013IB02830 |
申请日期 |
2013.08.30 |
申请人 |
CELLECTIS |
发明人 |
JUILLERAT, ALEXANDRE;DUCHATEAU, PHILIPPE |
分类号 |
C12N15/10;C12N15/63;C12N15/82 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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