发明名称 ARYL GPR120 RECEPTOR AGONISTS AND USES OF THE SAME
摘要 <p>PROBLEM TO BE SOLVED: To provide aryl GPR120 receptor agonists.SOLUTION: Aryl GPR120 receptor agonists are provided. These compounds are useful for treating metabolic disorders including type 2 diabetes and disorders accompanying blood glucose control deficiency. A method for treating disorders such as type 2 diabetes and other diseases and conditions, etc. by using one or multiple compounds or compositions of the present invention is also provided. The present invention also provides a method for raising the intracellular Calevel by using one or multiple compounds explained in the present specification. The compounds of the present invention can, furthermore, be used for stimulating the production of insulin and for stimulating the secretion of insulin, glucagon-like peptide 1 (GLP1), and glucose-dependent insulin-secreting polypeptide (GIP) among mammals, above all humans.</p>
申请公布号 JP2014132037(A) 申请公布日期 2014.07.17
申请号 JP20140082658 申请日期 2014.04.14
申请人 SHIMABAY THERAPEUTICS INC 发明人 MA JINGYUAN;AARON NOVACK;IMAD NASHASHIBI;PHUONGLY PHAM;CHRISTOPHER J RABBAT;SONG JIANGAO;SHI DONG FANG;ZHAO ZUCHUN;CHOI YUN-JUNG;CHEN XIN
分类号 C07D231/12;A61K31/341;A61K31/4025;A61K31/415;A61K31/4164;A61K31/4192;A61K31/42;A61K31/421;A61K31/422;A61K31/426;A61K31/433;A61K31/4439;A61K31/506;A61P3/00;A61P3/06;A61P3/10;A61P5/50;C07D231/20;C07D233/64;C07D249/06;C07D261/08;C07D263/32;C07D277/24;C07D285/06;C07D307/42;C07D401/04;C07D403/04;C07D409/04 主分类号 C07D231/12
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