| 发明名称 |
TRITERPENE GLYCOSIDE AND TRITERPENE COMPOSITIONS AND METHODS OF USING SAME |
| 摘要 |
In the present invention, different strategies are used to improve the bioavailability of triterpene glycosides and triterpenes including, for example, (a) a covalent approach involving modification with polyethylene glycol and (b) a formulation approach involving non-covalent encapsulation in antibody targeted pol(DL-lactic acid) nanoparticles. |
| 申请公布号 |
US2014199297(A1) |
申请公布日期 |
2014.07.17 |
| 申请号 |
US201414158616 |
申请日期 |
2014.01.17 |
| 申请人 |
Research Foundation of the City University of New York |
发明人 |
Einbond Linda Saxe;Raja Krishnaswami |
| 分类号 |
C07J71/00;A61K47/48;A61K31/58;A61K31/337;A61K39/395 |
主分类号 |
C07J71/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A PEGylated triterpenes glycoside or triterpene with improved bioavailability with the following formulaewherein R is OH or H, and wherein R1 is α-L-arabinoside and R2 is H, R1 is β-D-xyloside and R2 is H, or R1 is β-D-xyloside and R2 is Ac. |
| 地址 |
New York NY US |
