发明名称 COMBINATION
摘要 The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering -methyl-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimi dazole-4-carboxylic acid, or a pharmaceutically acceptable salt thereof, and N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)6,8-dimethy;-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, to a human in need thereof.
申请公布号 WO2014108837(A1) 申请公布日期 2014.07.17
申请号 WO2014IB58125 申请日期 2014.01.08
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED 发明人 BACHMAN, KURTIS EARL;GRESHOCK, JOEL DAVID;HARDWICKE, MARY ANN
分类号 A61K31/4375;A61K31/5377;A61P35/00 主分类号 A61K31/4375
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