METHODS AND SYSTEMS FOR OPTIMIZING LESION PLACEMENT TO MINIMIZE AND TREAT CARDIAC FIBRILLATION

摘要

Methods and systems for optimizing lesion placement to treat cardiac fibrillation in a patient include obtaining a map of one or more measurements indicative of a number and distribution of electrical circuit cores for a duration across a cardiac tissue substrate in response to electrical activity in the cardiac tissue substrate, identifying at least one region for the duration of the cardiac tissue substrate having a number of electrical circuit cores that is higher than a predetermined density threshold, generating a first sample set of lesions, the first sample set of lesions being registered onto the map, calculating and comparing a first total length of the first sample set of lesions to a predetermined length threshold, determining fitness of the first sample set of lesions, wherein fitness criteria is indicative of the level to which the sample set can terminate or at least minimize cardiac fibrillation.

主权项

1. A method for optimizing lesion placement to treat cardiac fibrillation in a patient, comprising:
obtaining a map of one or more measurements indicative of a number of electrical circuit cores and distribution of the electrical circuit cores for a duration across a cardiac tissue substrate in the patient's heart in response to electrical activity in the cardiac tissue substrate, said map being registered onto a representation of the patient's heart; identifying at least one region of the cardiac tissue substrate having a number of electrical circuit cores that is higher than a predetermined density threshold; generating a first sample set of lesions, said first sample set of lesions being registered onto the map; calculating a first total length of the first sample set of lesions by aggregating the length of each lesion in said first sample set of lesions; comparing the first total length to a predetermined length threshold; determining a level of optimization of the first sample set of lesions, wherein one or more optimization criteria are indicative of the level to which the sample set can at least one of minimize and terminate cardiac fibrillation and comprise at least one of the predetermined length threshold and the predetermined density threshold; generating successive sample sets of lesions if the one or more optimization criteria are not met by one or more previous sample sets of lesions; and repeating the steps of calculating a total length of each successive sample set of lesions, comparing the total length of each successive sample set of lesions to the predetermined length threshold, and determining a level of optimization of each successive sample set of lesions until the one or more optimization criteria are met.