| 发明名称 |
Enhancement of transport of therapeutic molecules across the blood brain barrier |
| 摘要 |
The invention is based, at least in part, on the finding that a dimeric version of a BBB-transmigrating antibody (e.g., theTMEM30A (CDC-50A) binding antibody, FC5) was found to greatly enhance transport across the BBB as compared to monovalent FC5 V |
| 申请公布号 |
AU2013207927(A1) |
申请公布日期 |
2014.07.17 |
| 申请号 |
AU20130207927 |
申请日期 |
2013.01.10 |
| 申请人 |
BIOGEN IDEC MA INC. |
发明人 |
FARRINGTON, GRAHAM K.;SISK, WILLIAM |
| 分类号 |
C07K16/28;A61K47/48;A61P25/00;C07K16/46 |
主分类号 |
C07K16/28 |
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