| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide an influenza virus vaccine, particularly a pediatric vaccine for the delivery to Langerhans cells.SOLUTION: The invention is based on the idea of using alternative routes of delivery for influenza vaccines except an intramuscular injection, more specifically routes that do not require as large a dose of antigen. Delivery of influenza antigen to the Langerhans cells is the route of choice according to the invention. This route has been found to be particularly useful for vaccinating patients who are naive to influenza virus (i.e. have not previously mounted an immune response to an influenza virus). This means that it is advantageous for immunizing young children.</p> |
