发明名称 COMBINATION
摘要 The present invention relates to a method of treating breast cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a breast cancer treatment method that includes administering 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof, and (S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7] indolizino [1,2-b]quinoline-3,14-(4H,12H)-dione, or a pharmaceutically acceptable salt thereof, to a human in need thereof.
申请公布号 EP2672969(A4) 申请公布日期 2014.07.16
申请号 EP20120742225 申请日期 2012.01.31
申请人 GLAXOSMITHKLINE INTELLECTUAL PROPERTY LIMITED;SUNNYBROOK RESEARCH INSTITUTE 发明人 KUMAR, RAKESH;KERBEL, ROBERT S.
分类号 A61K31/506;A61K31/4745;A61K45/06;A61P35/00;C07D231/56 主分类号 A61K31/506
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