A METHOD FOR DETERMINING THE PROPENSITY FOR CALCIFICATION

摘要

The present invention relates to a method for determining the propensity of a fluid for calcification.
The method is characterized by the following steps:
(i) adding a soluble calcium salt and a soluble phosphate salt to a sample of said fluid;
(ii) incubating said sample at conditions allowing the formation of calciprotein particles (CPPs); and
(iii) determining one or more of the following: (a) the rate of the formation of primary and/or secondary CPPs; (b) the amount of primary and/or secondary CPPs; and/or (c) the rate of the transition of primary CPPs into secondary CPPs, wherein an increase in one or more of (a), (b) and/or (c) of step (iii) indicates an increased propensity of said fluid for calcification.