发明名称 |
AGENTS FOR TREATING INFLAMMATION-RELATED CONDITIONS AND DISEASES |
摘要 |
Gene-modified, inflammation-specific monocytes that comprise a 1-alpha-hydroxylase gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme when the monocytes transdifferentiate into gene-modified, inflammation-specific macrophages. Gene-modified, inflammation-specific macrophages that comprise a 1-alpha-hydroxylase gene. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering gene-modified, inflammation-specific monocytes that comprise a 1-alpha-hydroxylase gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme when the monocytes transdifferentiate into gene-modified, inflammation-specific macrophages. |
申请公布号 |
EP2753365(A1) |
申请公布日期 |
2014.07.16 |
申请号 |
EP20130749628 |
申请日期 |
2013.02.13 |
申请人 |
LOMA LINDA UNIVERSITY;BAYLINK, DAVID J;LAU, KIN-HING, WILLIAM;QIN, XUEZHONG |
发明人 |
BAYLINK, DAVID, J.;LAU, KIN-HING, WILLIAM;QIN, XUEZHONG |
分类号 |
A61K35/15;A61K38/18;A61K38/30;A61K38/44;A61K45/06;A61K48/00;A61P29/00;C12N15/85;C12N15/86 |
主分类号 |
A61K35/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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