发明名称 |
METHOD FOR NONINVASIVE PREDICTION OR DIAGNOSIS OF INFLAMMATION AND INFECTION IN AMNIOTIC FLUID OF PATIENTS WITH PREMATURE RUPTURE OF MEMBRANES |
摘要 |
<p>Provided is a method for noninvasive prediction or diagnosis of inflammation and/or infection in amniotic fluid leaked through the cervix into the vagina to predict the concentration of inflammatory markers in the amniotic fluid inside uterus by measuring the concentration of inflammatory markers (various cytokines). Further provided is a method for prediction or diagnosis of inflammation and/or infection in amniotic fluid by measuring the concentration of markers (IL-6, IL-1βIL-8, MCP-1, GRO-α) in the amniotic fluid leaked through the cervix into the vagina in patients with premature rupture of membranes. The method can be performed more stably on pregnant women, as compared to the conventional method for prediction or diagnosis of inflammation and/or infection using invasively collected amniotic fluid.</p> |
申请公布号 |
EP2753934(A2) |
申请公布日期 |
2014.07.16 |
申请号 |
EP20120830732 |
申请日期 |
2012.09.05 |
申请人 |
SNU R&DB FOUNDATION;OB MED |
发明人 |
YOON, BO HYUN;PARK, JOONG SHIN;JUN, JONG KWAN;PARK, CHAN WOOK |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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