摘要 |
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease. |
申请人 |
VENTIRX PHARMACEUTICALS, INC.;ARRAY BIOPHARMA, INC. |
发明人 |
HOWBERT, JAMES, JEFFRY;HERSHBERG, ROBERT;BURGESS, LAURANCE E.;DOHERTY, GEORGE A.;EARY, CHARLES TODD;GRONEBERG, ROBERT D.;JONES, ZACHARY;LYSSIKATOS, JOSEPH P.;YANG, HONG WOON |