发明名称 Formulation composition for stabilizing fusion proteins with IgG Fc domain
摘要 The present invention relates to a composition for stabilizing a fusion protein of a physiologically active protein and an Fc domain, and more particularly to a method of stabilizing a fusion protein of a protein and an Fc domain using a composition containing an ammonium salt or a combination of an ammonium salt and succinate. The composition containing an ammonium salt or a combination of an ammonium salt and succinate according to the present invention can effectively inhibit the aggregation of the protein-Fc domain fusion protein, and thus enables the fusion protein to be stored for a long period of time. Accordingly, the composition can be widely used in the medical field that uses the protein-Fc domain fusion protein.
申请公布号 KR101419884(B1) 申请公布日期 2014.07.16
申请号 KR20130126295 申请日期 2013.10.23
申请人 发明人
分类号 A61K31/14;A61K31/205;A61K47/30;A61P19/02 主分类号 A61K31/14
代理机构 代理人
主权项
地址