发明名称 Compositions and methods for treatment and prevention of osteoarthritis
摘要 The present invention is in the fields of medicine, pharmaceuticals, neutraceuticals and rheumatology. The invention provides pharmaceutical compositions for the treatment and/or prevention of osteoarthritis in mammals, particularly humans, comprising sodium bicarbonate and calcium gluconate, and optionally comprising one or more additional components. The invention also provides methods of treating or preventing osteoarthritis by administering to a mammal, preferably via intraarticular injection, one or more compositions of the invention.
申请公布号 US8779006(B2) 申请公布日期 2014.07.15
申请号 US201113235149 申请日期 2011.09.16
申请人 Nucitec S.A. de C.V. 发明人 Amador Ricardo;Rosado Jorge L.;García-Padilla Sandra;Duarte-Vázquez Miguel Ángel
分类号 A61K47/12;A61K33/10;A61K33/14 主分类号 A61K47/12
代理机构 Sterne, Kessler, Goldstein & Fox P.L.L.C. 代理人 Sterne, Kessler, Goldstein & Fox P.L.L.C.
主权项 1. A method of treating osteoarthritis in a subject, comprising administering by intraarticular injection to a subject in need thereof a composition comprising sodium bicarbonate and calcium gluconate to treat the symptoms or underlying physiological causes of osteoarthritis, wherein said sodium bicarbonate is present at a concentration of from about 6%-8% (w/v).
地址 Queretaro MX