| 发明名称 | Compositions and methods for characterizing a myopathy | ||
| 摘要 | The invention provides compositions, methods, and kits diagnosing, monitoring, and otherwise characterizing a myopathy and for detecting the presence of autoantibodies in a biological sample. | ||
| 申请公布号 | US8778618(B2) | 申请公布日期 | 2014.07.15 |
| 申请号 | US201113641606 | 申请日期 | 2011.04.15 |
| 申请人 | The Johns Hopkins University | 发明人 | Casciola-Rosen Livia Angela;Christopher-Stine Lisa;Mammen Andrew;Rosen Antony |
| 分类号 | G01N33/53 | 主分类号 | G01N33/53 |
| 代理机构 | Edwards Wildman Palmer LLP | 代理人 | Edwards Wildman Palmer LLP ;Corless Peter F.;Emmons Richard B. |
| 主权项 | 1. A method for characterizing a myopathy in a subject, the method comprising detecting in a biological sample of the subject increased levels of an autoantibody that recognizes a 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) protein relative to a reference level. | ||
| 地址 | Baltimore MD US | ||