发明名称 |
Poxviral oncolytic vectors |
摘要 |
A poxvirus other than NYVAC but comprising a defective F4L and/or I4L gene and compositions comprising such poxvirus are useful for therapeutic purposes, and more particularly for the treatment of cancer. |
申请公布号 |
US8778328(B2) |
申请公布日期 |
2014.07.15 |
申请号 |
US200812743407 |
申请日期 |
2008.11.17 |
申请人 |
Transgene S.A. |
发明人 |
Erbs Philippe;Foloppe Johann |
分类号 |
A61K48/00;A61K39/275;A61K39/285;C12N7/01;C12N15/863 |
主分类号 |
A61K48/00 |
代理机构 |
Buchanan Ingersoll & Rooney PC |
代理人 |
Buchanan Ingersoll & Rooney PC |
主权项 |
1. An oncolytic poxvirus comprising a defective I4L and/or F4L gene and a defective J2R gene, wherein the poxvirus further comprises a suicide gene with the proviso that said poxvirus is not NYVAC. |
地址 |
Illkirch FR |