发明名称 Poxviral oncolytic vectors
摘要 A poxvirus other than NYVAC but comprising a defective F4L and/or I4L gene and compositions comprising such poxvirus are useful for therapeutic purposes, and more particularly for the treatment of cancer.
申请公布号 US8778328(B2) 申请公布日期 2014.07.15
申请号 US200812743407 申请日期 2008.11.17
申请人 Transgene S.A. 发明人 Erbs Philippe;Foloppe Johann
分类号 A61K48/00;A61K39/275;A61K39/285;C12N7/01;C12N15/863 主分类号 A61K48/00
代理机构 Buchanan Ingersoll & Rooney PC 代理人 Buchanan Ingersoll & Rooney PC
主权项 1. An oncolytic poxvirus comprising a defective I4L and/or F4L gene and a defective J2R gene, wherein the poxvirus further comprises a suicide gene with the proviso that said poxvirus is not NYVAC.
地址 Illkirch FR