发明名称 |
Foamy biomaterial for biological tissue repair |
摘要 |
A kit for producing a foamed biocompatible material includes a container configured to sustain a high pressure, and a tissue-repair composition placed in the container. The composition contains a biocompatible material, a liquid carrier, and a gas. The container has an internal pressure of greater than 1 atm and less than 250 atm, and includes a valve and a nozzle for releasing from the nozzle a foam formed of the composition upon opening the valve. Methods of producing and applying the biocompatible material are also disclosed. |
申请公布号 |
US8778883(B2) |
申请公布日期 |
2014.07.15 |
申请号 |
US200912618381 |
申请日期 |
2009.11.13 |
申请人 |
Industrial Technology Research Institute;National Taiwan University Hospital |
发明人 |
Liao Chun-Jen;Tseng Sheng-Hong;Liang Huang-Chien;Su Yi-Chun;Hsu Pei-Chi |
分类号 |
A61K38/39;A61K9/12;A61K38/01;A61K8/65 |
主分类号 |
A61K38/39 |
代理机构 |
Cesari and McKenna, LLP |
代理人 |
Cesari and McKenna, LLP |
主权项 |
1. A kit for producing a foamed biocompatible material for tissue repair, comprising:
a container configured to sustain a high pressure of greater than 1 atm and less than 250 atm, and a tissue-repair composition placed in the container, the composition containing a neutralized and homogeneous solution at pH 6-8 that includes a biocompatible material, wherein the biocompatible material consists of collagen at a concentration of 1%-10%, a liquid carrier that is water, physiological saline, or phosphate buffered saline, and a gas that is air, oxygen, nitrogen, or carbon dioxide, wherein the container has an internal pressure of greater than 1 atm and less than 250 atm, and includes a valve and a nozzle for releasing from the nozzle a foam formed of the composition upon opening the valve, and wherein the kit is free of a cross-linking agent. |
地址 |
Hsinchu TW |