发明名称 Foamy biomaterial for biological tissue repair
摘要 A kit for producing a foamed biocompatible material includes a container configured to sustain a high pressure, and a tissue-repair composition placed in the container. The composition contains a biocompatible material, a liquid carrier, and a gas. The container has an internal pressure of greater than 1 atm and less than 250 atm, and includes a valve and a nozzle for releasing from the nozzle a foam formed of the composition upon opening the valve. Methods of producing and applying the biocompatible material are also disclosed.
申请公布号 US8778883(B2) 申请公布日期 2014.07.15
申请号 US200912618381 申请日期 2009.11.13
申请人 Industrial Technology Research Institute;National Taiwan University Hospital 发明人 Liao Chun-Jen;Tseng Sheng-Hong;Liang Huang-Chien;Su Yi-Chun;Hsu Pei-Chi
分类号 A61K38/39;A61K9/12;A61K38/01;A61K8/65 主分类号 A61K38/39
代理机构 Cesari and McKenna, LLP 代理人 Cesari and McKenna, LLP
主权项 1. A kit for producing a foamed biocompatible material for tissue repair, comprising: a container configured to sustain a high pressure of greater than 1 atm and less than 250 atm, and a tissue-repair composition placed in the container, the composition containing a neutralized and homogeneous solution at pH 6-8 that includes a biocompatible material, wherein the biocompatible material consists of collagen at a concentration of 1%-10%, a liquid carrier that is water, physiological saline, or phosphate buffered saline, and a gas that is air, oxygen, nitrogen, or carbon dioxide, wherein the container has an internal pressure of greater than 1 atm and less than 250 atm, and includes a valve and a nozzle for releasing from the nozzle a foam formed of the composition upon opening the valve, and wherein the kit is free of a cross-linking agent.
地址 Hsinchu TW