| 发明名称 |
Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor |
| 摘要 |
The present invention relates to new biphenyl-3-carboxylic acid modulators of beta-3-adrenoceptor activity, pharmaceutical compositions thereof, and methods of use thereof, wherein R1-R23 are independently selected from the group consisting of hydrogen and deuterium; and at least one of R1-R23 is deuterium.; |
| 申请公布号 |
US8778998(B2) |
申请公布日期 |
2014.07.15 |
| 申请号 |
US201012757444 |
申请日期 |
2010.04.09 |
| 申请人 |
Auspex Pharmaceuticals, Inc. |
发明人 |
Zhang Chengzhi |
| 分类号 |
A61K31/195;C07C59/48 |
主分类号 |
A61K31/195 |
| 代理机构 |
|
代理人 |
Bennett Dennis A.;Sertic Michael S. |
| 主权项 |
1. A composition comprising compounds having the structural formulaor a pharmaceutically acceptable salt thereof, wherein:
wherein each position represented as D has deuterium enrichment of no less than about 10%. |
| 地址 |
Vista CA US |
