发明名称 RESPONSIVENESS TO ANGIOGENESIS INHIBITORS.
摘要 The invention is concerned with a method of determining whether a patient is more suitably treated by a therapy with an angiogenesis inhibitor, such as bevacizumab, by determing the genotype of VEGFR-1 gene. The invention further relates to a pharmaceutical composition comprising an angiogenesis inhibitor, such as bevacizumab, for the treatment of a patient suffering from cancer based on the genotype of VEGFR-1 gene. The invention further relates to a method for improving the treatment effect of chemotherapy of a patient suffering from cancer by adding an angiogenesis inhibitor, such as bevacizumab, based on the genotype of VEGFR-1 gene.
申请公布号 MX2014006186(A) 申请公布日期 2014.07.14
申请号 MX20140006186 申请日期 2012.11.19
申请人 F. HOFFMANN-LA ROCHE AG 发明人 PETER CARMELIET;SANNE LYSBET DE HAAS;DIETHER LAMBRECHTS;STEFAN SCHERER
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
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