发明名称 |
poly(ethylene oxide)-poly(propylene oxide) copolymer and Photosensitizer Covalent Complex for Photodynamic Therapy |
摘要 |
PURPOSE: A composite for photodynamic therapy is provided to ensure excellent cancer tissue selectivity and biodegradation and to treat and diagnose cancer. CONSTITUTION: A composite for photodynamic therapy contains a biocompatible polymer and a photosensitizer which are combined by ester bond. The biocompatible polymer is a poly(ethylene oxide)-poly(propylene oxide) amphipathic block copolymer. The composite is a nanoparticle in an aqueous system. A method for preparing the composite comprises: a step of dissolving the poly(ethylene oxide)-poly(propylene oxide) amphipathic block copolymer in an organic solvent; a step of dissolving the photosensitizer and a catalyst; and a step of reacting. |
申请公布号 |
KR101419124(B1) |
申请公布日期 |
2014.07.11 |
申请号 |
KR20120102146 |
申请日期 |
2012.09.14 |
申请人 |
|
发明人 |
|
分类号 |
A61K9/16;A61K47/30;A61K47/48;A61K49/12 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|