发明名称 |
USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) |
摘要 |
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. |
申请公布号 |
US2014194446(A1) |
申请公布日期 |
2014.07.10 |
申请号 |
US201314091196 |
申请日期 |
2013.11.26 |
申请人 |
Pharmacyclics, Inc. |
发明人 |
BUGGY Jospeh J.;Elias Laurence;Fyfe Gwen;Hedrick Eric;Loury David J.;Mody Tarak D. |
分类号 |
C07D487/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Sunnyvale CA US |