CARRIER PELLETS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF

摘要

The invention relates to a method for the production of carrier pellets for pharmaceutical active substances. Likewise, the invention relates to such carrier pellets and also to pharmaceutical formulations containing these. The carrier pellets according to the invention are used for transporting and releasing pharmaceutical active substances, in particular in the human body.

主权项

1. A method for the production of carrier pellets for a pharmaceutically active substance, the method comprising:
a) producing a liquid formulation by dissolving, dispersing, or a combination of dissolving and dispersing at least one physiologically well-tolerated pH regulator in at least one solvent or emulsifier; b) introducing the liquid formulation into a fluidized-bed or spouted-bed unit using at least one nozzle; c) forming essentially spherical carrier pellets by spray granulation in the unit wherein the solvent is evaporated by a drying gas flow; and d) discharging the carrier pellets from the unit.