发明名称 |
INDIVIDUALIZED VACCINES FOR CANCER |
摘要 |
The present invention relates to a patient-specific tumor treatment targeting individual expression patterns of tumor antigens, in particular shared tumor antigens, and individual tumor mutations. In one aspect, the present invention relates to a method for preventing or treating cancer in a patient comprising the steps of: (i) inducing a first immune response against one or more tumor antigens in the patient, and (ii) inducing a second immune response against one or more tumor antigens in the patient wherein the second immune response is specific for cancer specific somatic mutations present in cancer cells of the patient. |
申请公布号 |
WO2014082729(A9) |
申请公布日期 |
2014.07.10 |
申请号 |
WO2013EP03559 |
申请日期 |
2013.11.26 |
申请人 |
BIONTECH AG;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZGEMEINNÜTZIGE GMBH |
发明人 |
SAHIN, UGUR;PARET, CLAUDIA;VORMBROCK, KIRSTEN;BENDER, CHRISTIAN;DIEKMANN, JAN |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|