Treatment of Graft-Versus-Host Disease Disorders using RAR Antagonists

摘要

The present specification provides RAR antagonist compounds, compositions comprising such RAR antagonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such RAR antagonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection.

主权项

1. A method of treating a transplant rejection, the method comprising administering to an individual in need thereof a therapeutically effective amount of a RAR antagonist, thereby treating the transplant rejection in the individual.