发明名称 |
POLYMERIC FORMS OF H-NOX PROTEINS |
摘要 |
The invention provides polymeric H-NOX proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric H-NOX proteins. Polymeric H-NOX proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen. The invention also provides the use of H- NOX proteins as radiosensitizers for the treatment of brain cancers. |
申请公布号 |
WO2014107171(A1) |
申请公布日期 |
2014.07.10 |
申请号 |
WO2013US20602 |
申请日期 |
2013.01.07 |
申请人 |
OMNIOX, INC. |
发明人 |
KAPP, GREGORY;SERWER, LAURA;LEMOAN, NATACHA;CARY, STEPHEN, P.L. |
分类号 |
C07K14/795;A61K38/41;A61P7/06;A61P35/00;C07K19/00 |
主分类号 |
C07K14/795 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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