发明名称 |
N-demethylation of 6-keto morphinans |
摘要 |
The present invention provides processes for the demethylation of an N-methyl morphinan comprising a ketone functional group. In particular, the invention provides methods for the protection of the ketone functional group such that impurities are not generated during the demethylation of the N-methyl morphinan. |
申请公布号 |
AU2011285840(B2) |
申请公布日期 |
2014.07.10 |
申请号 |
AU20110285840 |
申请日期 |
2011.08.03 |
申请人 |
MALLINCKRODT LLC |
发明人 |
WANG, PETER X.;JIANG, TAO;BERBERICH, DAVID W.;LIAO, SUBO |
分类号 |
C07D489/08 |
主分类号 |
C07D489/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|