Biological materials and uses thereof

摘要

The invention provides binding molecules, including antibody molecules which selectively bind to a cell surface antigen of a target cell, and wherein the binding molecules, on binding the cell surface antigen, induce apoptosis of the target cell. There is also provided methods of and pharmaceutical compositions for apoptosis induction and uses thereof. scFv F1 scFv B1 1Goo 7o 6 0 00 GooSo 1000 0 200 400 900 800 1000 FSC44:: FSC*sght FSC-H. PSC-ieigt scFv F1 scFvBl1 1 10 100 10o0w 10 100 1000 FL14H= Annexin FL 4t=Anneil Figure 2