TOPICAL ANTI-INFLAMMATORY COMPOSITIONS AND USES THEREOF

摘要

Disclosed are pharmaceutical compositions and topical formulations thereof that include multiple, phytochemically-active, nutraceutical compounds, and that possess potent anti-inflammatory and extracellular matrix-stabilizing properties both in vitro and in vivo. Also disclosed are prophylactic and therapeutic methods, as well as dosing regimens and medicaments for use in preventing chronic disease, for treating acute or long-term inflammatory-mediated conditions in affected or at-risk subjects, and for stabilizing one or more components of the mammalian extracellular matrix.

主权项

1. An aqueous composition comprising:
a) one or more catechins, catechin derivatives, or catechin analogs, agonists, or antagonists thereof; b) one or more curcuminoids, curcuminoid derivatives, or curcuminoid analogs, agonists, or antagonists thereof; c) one or more isothiocyanates, isothiocyanate derivatives, or isothiocyanate analogs, agonists, or antagonists thereof; d) one or more stilbenoids, stilbenoid derivatives, or stilbenoid analogs, agonists, or antagonists thereof; and e) at least one therapeutic essential oil; wherein each of which present in the composition in an anti-inflammatory-effective amount.