PHARMACEUTICAL INHALED MEDICATION FOR TREATMENT OF BRONCHIAL ASTHMA AND CHRONIC OBSTRUCTIVE LUNG DISEASE, CONTAINING MICRONISED TIOTROPIUM BROMIDE AS ACTIVE SUBSTANCE AND METHOD OF ITS PRODUCTION

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to medicine and the pharmaceutical industry and describes a pharmaceutical inhaled medication for treatment of bronchial asthma and chronic obstructive lung disease, containing micronised tiotropium bromide as an active substance, and which contains as a carrier lactose with the average particle size of 120-200 mcm, sodium benzoate, sieved with a bulk density within the range of 0.30-0.50 g/cmand sodium benzoate micronised with the average particle size of 0.5-10 mcm with a specified content of components per a dose of medication.EFFECT: invention provides higher percent of a respirable fraction of the active substance and, therefore, higher pharmacological activity.3 cl, 10 ex